She played the role of Kathy Veck, owner of an oil company. In 2012, Marshall guest starred in an episode of CSI: Crime Scene Investigation. Marshall had a guest role in the hit drama House, playing Julia, sister of Lisa Cuddy. The show was her first to be picked up for a second season. She and Jay Mohr played a divorced couple sparring while trying to be loving parents to their two children. Marshall starred on the CBS sitcom Gary Unmarried. In 2008, Marshall joined the crime drama Shark as a recurring character.
She also was seen in the FX series Nip/Tuck as an insecure actress who dated Dr.
In 2007, Marshall appeared in the Showtime series Californication. Marshall's next main role came in the sitcom Out of Practice. In October, she had a four-episode role in Veronica Mars, (created by Rob Thomas), and she reprised the role toward the end of season two.
In 2004, Marshall appeared in an episode of the tv show Miss Match, but the series was cancelled before it aired. Marshall also had a secondary role in the Steve Martin- Bonnie Hunt remake of Cheaper by the Dozen and a cameo appearance in Break a Leg, which starred her husband Danny Nucci. Hidden Hills was an offbeat comedy about three families in suburbia. In 2002, she guest starred on Just Shoot Me! as the daughter of Nina Van Horn. In 2000, Marshall returned to television screens: first with a three-episode guest appearance as a porn star and love interest for Jeremy ( Joshua Malina) on Aaron Sorkin's Sports Night, and then in Cursed (a.k.a. Kelley's Snoops about an unconventional detective agency. Claire Allen, a psychiatrist supervising a man named Trevor ( Jeremy Piven) who thinks he is Cupid. Marshall was on Rob Thomas's Cupid, premiering in 1998. Marshall has been cast in several pilots that were not picked up, including the Elizabeth Lackey series Cooking Lessons and Rob Thomas's Sticks. The same year, she landed a recurring role on Spin City and starred with Bette Midler and Dennis Farina in the film That Old Feeling, where her character fell in love with the paparazzo played by Danny Nucci. After a few years in B movies, Marshall gained a role on 1997's Chicago Sons. Abby O'Reardon, an evil scientist who rejuvenates her boss (and later becomes his mother) and is bent on turning grown men into babies. World, directed by William Maloneas, as Dr. In 1995, Marshall starred in the science fiction cult classic W.E.I.R.D. In 1994, she got her first sitcom role on Wild Oats.
Later in 1992, she appeared in the movie Hellraiser III: Hell on Earth as Terri. In 1992, Marshall had a three-episode guest role on The Wonder Years and later guest-starred on shows such as Seinfeld, Nash Bridges, Grapevine and Diagnosis: Murder. In 1991, she guest-starred on Superboy with a young Clark Kent before he called himself Superman, playing the villainous Christina Riley, a woman who is, in secret, a werewolf. In 1990, Marshall had a guest role as Iris West, the love interest of Flash (Barry Allen) in the pilot episode on the short-lived Flash.